Karthus is ranked Tier and has a 60.00% win rate in LoL AR URF Patch 25.04. We've analyzed 5 Karthus games to compile our statistical Karthus AR URF Build Guide. For items, our build recommends: Malignance, Liandry's Torment, Shadowflame, Ionian Boots of Lucidity, Rabadon's Deathcap, and Void Staff. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Amplifying Tome, Health Potion, and Stealth Ward. Karthus's Best AR URF matchups include Lux.
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Karthus Summoner Spells


Win %
Pick %
60%
100%
67%
60%

50%
40%
Karthus Starting Items
Win %
Buy %


2

33%
60%
Karthus Runes
Win %
Pick %
100%
20%
100%
20%
33%
60%
Karthus Items

75%

33%

75%

0%

67%

100%

60%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order





















Karthus Trinkets
Win %
Buy %

60%
100%
Karthus Boots
Win %
Buy %

0%
20%

0%
40%
Karthus Situational Items
Win %
Buy %

0%
20%