Karthus is ranked Tier and has a 54.55% win rate in LoL AR URF Patch 25.04. We've analyzed 11 Karthus games to compile our statistical Karthus AR URF Build Guide. For items, our build recommends: Malignance, Horizon Focus, Stormsurge, Liandry's Torment, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ghost. Starting items should include Amplifying Tome and Health Potion.
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Karthus Summoner Spells


Win %
Pick %
60%
91%
50%
55%

67%
27%

50%
18%

0%
9%
Karthus Starting Items
Win %
Buy %


75%
36%
Karthus Runes
Win %
Pick %
63%
41%
50%
52%
Karthus Items

71%

50%

50%

56%

50%

60%

50%

0%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order























Karthus Trinkets
Win %
Buy %

50%
55%

100%
18%

25%
36%
Karthus Boots
Win %
Buy %

100%
9%

33%
27%

100%
9%
Karthus Situational Items
Win %
Buy %

50%
18%

50%
18%

50%
18%

100%
9%

100%
9%

0%
9%