Kai'Sa Mid Lane is ranked Off Meta Tier and has a 48.04% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 331 Kai'Sa Mid Lane games to compile our statistical Kai'Sa Spellbook Build Guide. For items, our build recommends: Statikk Shiv, Berserker's Greaves, Guinsoo's Rageblade, Nashor's Tooth, Rabadon's Deathcap, and Zhonya's Hourglass. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Placeholder. Starting items should include Scout's Slingshot, Long Sword, and Stealth Ward. Kai'Sa's Best Spellbook Mid Lane matchups include Diana, Kassadin, and Twisted Fate. Kai'Sa's Best Spellbook Mid Lane counters are Lux, Akali, and Irelia.
Kai'Sa Summoner Spells




Kai'Sa Starting Items







Kai'Sa Runes
Kai'Sa Items








Kai'Sa Skill Order
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Kai'Sa Item Purchase Order

























Kai'Sa Ultimate Spellbook Stats
























































































Kai'Sa Trinkets



Kai'Sa Boots






Kai'Sa Situational Items





