Karthus Support is ranked B Tier and has a 48.42% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 158 Karthus Support games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Sorcerer's Shoes, Malignance, Liandry's Torment, Shadowflame, Zaz'Zak's Realmspike, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include World Atlas, Sapphire Crystal, Health Potion, and Stealth Ward. Karthus's Best Spellbook Support matchups include Leona, Malphite, and Nautilus. Karthus's Best Spellbook Support counters are Blitzcrank, Pyke, and Thresh.
Karthus Summoner Spells






Karthus Starting Items







Karthus Runes
Karthus Items








Karthus Skill Order
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Karthus Item Purchase Order




















Karthus Ultimate Spellbook Stats
























































































Karthus Trinkets



Karthus Boots




Karthus Support Items


