Vayne ADC is ranked A Tier and has a 52.12% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 1000 Vayne ADC games to compile our statistical Vayne Spellbook Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Kraken Slayer, Guinsoo's Rageblade, Terminus, and Wit's End. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Doran's Blade, Long Sword, Health Potion, and Stealth Ward. Vayne's Best Spellbook ADC matchups include Lucian, Heimerdinger, and Kalista. Vayne's Best Spellbook ADC counters are Seraphine, Aurelion Sol, and Singed.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Item Purchase Order
1100
3200
3100
3000300028002000Vayne Ultimate Spellbook Stats
Vayne Trinkets
Vayne Boots
Vayne Situational Items
Average Support Duo Queue Champions for Vayne ADC in Ultimate Spellbook(49% - 51% win rate with Vayne)
Even ADC Matchups for Vayne ADC in Ultimate Spellbook(49% - 51% win rate for Vayne)
Even Support Matchups for Vayne ADC in Ultimate Spellbook(49% - 51% win rate for Vayne)
