Lissandra Mid Lane is ranked A Tier and has a 49.69% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 585 Lissandra Mid Lane games to compile our statistical Lissandra Spellbook Build Guide. For items, our build recommends: Malignance, Luden's Companion, Sorcerer's Shoes, Shadowflame, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Placeholder. Starting items should include Amplifying Tome, Sapphire Crystal, Refillable Potion, Control Ward, and Stealth Ward. Lissandra's Best Spellbook Mid Lane matchups include Hwei, Kai'Sa, and Varus. Lissandra's Best Spellbook Mid Lane counters are Azir, Karma, and Pantheon.
Lissandra Summoner Spells




Lissandra Starting Items









Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Item Purchase Order


























Lissandra Ultimate Spellbook Stats
























































































Lissandra Trinkets



Lissandra Boots






Lissandra Situational Items





