Kai'Sa Mid Lane is ranked Off Meta Tier and has a 43.25% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 573 Kai'Sa Mid Lane games to compile our statistical Kai'Sa Spellbook Build Guide. For items, our build recommends: Statikk Shiv, Berserker's Greaves, Manamune, Kraken Slayer, Guinsoo's Rageblade, and Nashor's Tooth. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Tear of the Goddess, Glowing Mote, Health Potion, and Stealth Ward. Kai'Sa's Best Spellbook Mid Lane matchups include Twisted Fate, Zoe, and Aurelion Sol. Kai'Sa's Best Spellbook Mid Lane counters are Yasuo, Brand, and Corki.
Kai'Sa Summoner Spells






Kai'Sa Starting Items








Kai'Sa Runes
Kai'Sa Items








Kai'Sa Skill Order
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Kai'Sa Item Purchase Order

























Kai'Sa Ultimate Spellbook Stats
























































































Kai'Sa Trinkets



Kai'Sa Boots






Kai'Sa Situational Items





