Lissandra Mid Lane is ranked S Tier and has a 50.42% win rate in LoL Swiftplay Patch 25.05. We've analyzed 195 Lissandra Mid Lane games to compile our statistical Lissandra Swiftplay Build Guide. For items, our build recommends: Malignance, Luden's Companion, Sorcerer's Shoes, Zhonya's Hourglass, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Doran's Ring, Health Potion, and Oracle Lens. Lissandra's Best Swiftplay Mid Lane matchups include Aurora, Talon, and Katarina. Lissandra's Best Swiftplay Mid Lane counters are Ahri, Heimerdinger, and Kassadin.
Lissandra Summoner Spells






Lissandra Starting Items






Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Item Purchase Order


























Lissandra Trinkets



Lissandra Boots






Lissandra Situational Items





