Karthus Mid Lane is ranked Off Meta Tier and has a 53.42% win rate in LoL Swiftplay Patch 25.07. We've analyzed 567 Karthus Mid Lane games to compile our statistical Karthus Swiftplay Build Guide. For items, our build recommends: Sorcerer's Shoes, Blackfire Torch, Malignance, Liandry's Torment, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Swiftplay Mid Lane matchups include Annie, Hwei, and Vladimir. Karthus's Best Swiftplay Mid Lane counters are Cassiopeia, Heimerdinger, and Xerath.
Karthus Summoner Spells
Karthus Starting Items
Karthus Runes
Karthus Items
Karthus Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Karthus Item Purchase Order
1100
2800
2700
3000
32003600
750Karthus Trinkets
Karthus Boots
Karthus Situational Items
Average Jungle Duo Queue Champions for Karthus Mid Lane in Swiftplay(49% - 51% win rate with Karthus)
Even Mid Lane Matchups for Karthus Mid Lane in Swiftplay(49% - 51% win rate for Karthus)
