Tier: Off MetaWin50.53%Role6.30%Pick0.11%Ban3.83%Games: 44KDA: 1.73Score: 47.60
Karthus Mid Lane is ranked Off Meta Tier and has a 50.53% win rate in LoL Patch 25.08. We've analyzed 44 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Symbiotic Soles, Blackfire Torch, Liandry's Torment, Shadowflame, Rabadon's Deathcap, and Void Staff. For runes, the strongest choice is Sorcery (Primary) with Summon Aery (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Exhaust and Flash. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Hwei and Sylas.
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Karthus Summoner Spells


Win %
Pick %
52%
70%
41%
50%

62%
30%

44%
36%

67%
7%

100%
5%
Karthus Starting Items
Win %
Buy %


2

51%
80%

50%
9%
Karthus Runes
Win %
Pick %
61%
24%
47%
29%
51%
22%
51%
18%
Karthus Items

55%

58%

60%

44%

65%

65%

62%

83%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order























Karthus Trinkets
Win %
Buy %

62%
59%

29%
48%

40%
11%
Karthus Boots
Win %
Buy %

55%
45%

48%
52%
Karthus Situational Items
Win %
Buy %

45%
25%

100%
7%

100%
7%

100%
2%

100%
2%

100%
2%