Tier: Off MetaWin52.25%Role7.16%Pick0.17%Ban2.08%Games: 462KDA: 2.00Score: 52.03
Karthus Mid Lane is ranked Off Meta Tier and has a 52.25% win rate in LoL Patch 25.07. We've analyzed 462 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Blackfire Torch, Malignance, Sorcerer's Shoes, Liandry's Torment, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Mel, Gangplank, and Gragas. Karthus's Best Mid Lane counters are Aurelion Sol, Ekko, and Taliyah.
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Karthus Summoner Spells


Win %
Pick %
51%
73%
53%
58%

53%
37%

57%
25%

53%
3%

46%
3%
Karthus Starting Items
Win %
Buy %


2

53%
68%


59%
4%
Karthus Runes
Win %
Pick %
51%
39%
56%
18%
57%
15%
55%
5%
Karthus Items

56%

52%

54%

55%

63%

58%

52%

69%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order


























Karthus Trinkets
Win %
Buy %

52%
84%

55%
28%

64%
7%
Karthus Boots
Win %
Buy %

54%
75%

60%
5%

41%
4%

50%
1%

100%
0%

0%
0%
Karthus Situational Items
Win %
Buy %

48%
17%

61%
13%

82%
6%

68%
6%

43%
6%

46%
5%