Tier: SWin51.94%Role85.64%Pick10.40%Ban10.17%Games: 38438KDA: 2.26Score: 61.92
Vayne ADC is ranked S Tier and has a 51.94% win rate in LoL Patch 25.04. We've analyzed 38438 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Kraken Slayer, Guinsoo's Rageblade, Terminus, and Wit's End. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best ADC matchups include Karthus, Cassiopeia, and Kalista. Vayne's Best ADC counters are Singed and Jinx.
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Vayne Summoner Spells


Win %
Pick %
52%
100%
52%
77%

52%
8%

52%
5%

48%
4%

52%
4%
Vayne Starting Items
Win %
Buy %



52%
90%



53%
1%
Vayne Runes
Win %
Pick %
53%
71%
49%
17%
50%
2%
51%
1%
Vayne Items

53%

53%

54%

56%

57%

57%

51%

54%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order






























Vayne Trinkets
Win %
Buy %

51%
79%

55%
50%

51%
6%
Vayne Boots
Win %
Buy %

53%
88%

52%
3%

55%
1%

48%
1%

43%
0%

63%
0%
Vayne Situational Items
Win %
Buy %

51%
10%

56%
8%

58%
7%

55%
6%

56%
6%

60%
3%