Tier: AWin43.91%Role10.92%Pick0.23%Ban0.70%Games: 49KDA: 2.38Score: 46.52
Karthus Mid Lane is ranked A Tier and has a 43.91% win rate in LoL Patch 9.24. We've analyzed 49 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Rod of Ages, Sorcerer's Shoes, Luden's Echo, Morellonomicon, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Health Potion, Doran's Ring, Refillable Potion, Corrupting Potion, and Warding Totem (Trinket). Karthus's Best Mid Lane matchups include Vladimir. Karthus's Best Mid Lane counters are Irelia and Yasuo.
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Karthus Summoner Spells


Win %
Pick %
61%
100%
60%
82%

67%
6%

67%
6%

100%
2%

50%
4%
Karthus Starting Items

57%

57%

71%

67%

61%
Karthus Runes
Win %
Pick %
61%
45%
54%
16%
70%
7%
79%
6%
Karthus Items

54%

59%

70%

47%

61%

75%

60%

100%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Trinkets
Win %
Buy %

60%
96%

56%
33%

60%
10%
Karthus Boots
Win %
Buy %

59%
104%