Vayne Mid Lane is ranked Off Meta Tier and has a 34.60% win rate in LoL Patch 7.24. We've analyzed 48 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of the Ruined King, Statikk Shiv, Infinity Edge, Duskblade of Draktharr, and Rapid Firecannon. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Health Potion, Doran's Blade, Long Sword, Control Ward, and Warding Totem (Trinket). Vayne's Best Mid Lane counters are Fizz.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Jungle Duo Queue Champions for Vayne Mid Lane(49% - 51% win rate with Vayne)
Below Average Jungle Duo Queue Champions for Vayne Mid Lane(under 49% win rate with Vayne)
Best Mid Lane Champions to Counter Vayne Mid Lane(under 49% win rate for Vayne)
Even Mid Lane Matchups for Vayne Mid Lane(49% - 51% win rate for Vayne)
