Vayne Mid Lane is ranked Off Meta Tier and has a 36.53% win rate in LoL Patch 7.24. We've analyzed 115 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Statikk Shiv, Blade of the Ruined King, Infinity Edge, Rapid Firecannon, and Phantom Dancer. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Health Potion, Doran's Blade, Long Sword, Doran's Shield, and Warding Totem (Trinket). Vayne's Best Mid Lane matchups include Ahri, Kassadin, and Zoe. Vayne's Best Mid Lane counters are Diana, Ryze, and Xerath.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Jungle Duo Queue Champions for Vayne Mid Lane(49% - 51% win rate with Vayne)
Even Mid Lane Matchups for Vayne Mid Lane(49% - 51% win rate for Vayne)
