Lissandra Mid Lane is ranked C Tier and has a 49.25% win rate in LoL Patch 7.24. We've analyzed 1548 Lissandra Mid Lane games to compile our statistical Lissandra Build Guide. For items, our build recommends: Rod of Ages, Sorcerer's Shoes, Hextech Protobelt-01, Morellonomicon, Zhonya's Hourglass, and Liandry's Torment. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and <pathBonus><pathSorcery>Sorcery</pathSorcery> + <pathInspiration>Inspiration</pathInspiration> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Health Potion, Doran's Ring, Refillable Potion, The Dark Seal, and Warding Totem (Trinket). Lissandra's Best Mid Lane matchups include Kassadin, Karthus, and Gangplank. Lissandra's Best Mid Lane counters are Morgana, Ziggs, and Akali.
Lissandra Summoner Spells






Lissandra Starting Items





Lissandra Runes
Lissandra Items








Lissandra Skill Order
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![]() | R | R | R |
Lissandra Trinkets




Lissandra Boots





