Tier: Off MetaWin61.76%Role1.24%Pick0.17%Ban9.95%Games: 34KDA: 2.53Score: 54.40
Vayne Mid Lane is ranked Off Meta Tier and has a 61.76% win rate in LoL Patch 25.05. We've analyzed 34 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Trinity Force, Kraken Slayer, Guinsoo's Rageblade, and Wit's End. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include Mel and Zed. Vayne's Best Mid Lane counters are Galio.
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Vayne Summoner Spells


Win %
Pick %
62%
100%
63%
47%

67%
26%

67%
9%

50%
12%

50%
6%
Vayne Starting Items
Win %
Buy %



67%
62%


67%
9%
Vayne Runes
Win %
Pick %
85%
46%
34%
33%
100%
3%
Vayne Items

62%

61%

83%

50%

72%

56%

57%

100%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order






























Vayne Trinkets
Win %
Buy %

57%
82%

69%
38%

33%
9%
Vayne Boots
Win %
Buy %

62%
76%

67%
9%

67%
9%
Vayne Situational Items
Win %
Buy %

71%
21%

100%
3%

100%
3%

100%
3%

100%
3%

100%
3%