Tier: Off MetaWin32.87%Role12.16%Pick0.13%Ban0.42%Games: 89KDA: 1.94Score: 45.86
Karthus Mid Lane is ranked Off Meta Tier and has a 32.87% win rate in LoL Patch 25.04. We've analyzed 89 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Malignance, Sorcerer's Shoes, Liandry's Torment, Archangel's Staff, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Aurora and Azir. Karthus's Best Mid Lane counters are Sylas and Veigar.
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Karthus Summoner Spells
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Win %
Pick %
43%
81%
37%
58%

37%
21%

27%
29%

100%
4%

0%
6%
Karthus Starting Items
Win %
Buy %


2

38%
47%


2

26%
35%
Karthus Runes
Win %
Pick %
38%
51%
83%
4%
22%
18%
53%
6%
Karthus Items

45%

44%

49%

45%

58%

56%

38%

90%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order


























Karthus Trinkets
Win %
Buy %

38%
92%

100%
8%

31%
15%
Karthus Boots
Win %
Buy %

44%
69%

100%
1%

0%
4%
Karthus Situational Items
Win %
Buy %

26%
43%

56%
10%

42%
13%

75%
4%

67%
3%

25%
4%