Tier: Off MetaWin39.05%Role3.05%Pick0.10%Ban15.16%Games: 145KDA: 1.75Score: 45.14
Karthus Mid Lane is ranked Off Meta Tier and has a 39.05% win rate in LoL Patch 25.08. We've analyzed 145 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Rod of Ages, Blackfire Torch, Sorcerer's Shoes, Liandry's Torment, Shadowflame, and Zhonya's Hourglass. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Sylas, Azir, and Fizz. Karthus's Best Mid Lane counters are Taliyah, Orianna, and Irelia.
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Karthus Summoner Spells


Win %
Pick %
47%
95%
41%
70%

59%
30%

50%
3%

0%
1%

0%
1%
Karthus Starting Items
Win %
Buy %


2

47%
91%


50%
1%
Karthus Runes
Win %
Pick %
45%
41%
56%
18%
41%
17%
62%
1%
Karthus Items

42%

49%

46%

46%

44%

52%

45%

57%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order


























Karthus Trinkets
Win %
Buy %

45%
71%

50%
54%

50%
15%
Karthus Boots
Win %
Buy %

46%
96%

50%
1%

0%
1%

0%
1%
Karthus Situational Items
Win %
Buy %

67%
12%

40%
10%

36%
8%

57%
5%

67%
4%

75%
3%