Tier: DWin31.91%Role13.17%Pick0.39%Ban3.10%Games: 47KDA: 2.12Score: 42.68
Karthus Mid Lane is ranked D Tier and has a 31.91% win rate in LoL Patch 10.25. We've analyzed 47 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Mercury's Treads, Liandry's Anguish, Rabadon's Deathcap, Zhonya's Hourglass, Chemtech Putrifier, and Seraph's Embrace. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Sapphire Crystal, Refillable Potion, and Oracle Lens. Karthus's Best Mid Lane counters are Akali, Tristana, and Yasuo.
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Karthus Summoner Spells


Win %
Pick %
30%
98%
30%
70%

45%
23%

33%
6%

0%
2%
Karthus Starting Items
Win %
Buy %



42%
26%


2

27%
23%
Karthus Runes
Win %
Pick %
26%
54%
43%
27%
100%
2%
0%
2%
Karthus Items

30%

34%

75%

25%

41%

40%

36%

50%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order























Karthus Trinkets
Win %
Buy %

36%
60%

30%
43%

29%
15%
Karthus Boots
Win %
Buy %

30%
57%

32%
40%

0%
2%
Karthus Mythic Items
Win %
Buy %

34%
68%

33%
19%

50%
4%