Tier: Off MetaWin54.72%Role4.52%Pick0.58%Ban7.40%Games: 53KDA: 2.04Score: 52.71
Vayne Mid Lane is ranked Off Meta Tier and has a 54.72% win rate in LoL Patch 9.24. We've analyzed 53 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of the Ruined King, Guinsoo's Rageblade, Phantom Dancer, Infinity Edge, and Guardian Angel. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Shield, Doran's Blade, Cull, and Warding Totem (Trinket). Vayne's Best Mid Lane matchups include Lux, Mordekaiser, and Twisted Fate.
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Vayne Summoner Spells


Win %
Pick %
55%
100%
52%
51%

41%
32%

100%
6%

75%
8%

100%
2%
Vayne Starting Items

56%

52%

67%

67%

56%
Vayne Runes
Win %
Pick %
62%
38%
49%
42%
47%
9%
100%
2%
Vayne Items

54%

57%

68%

56%

83%

100%

54%

100%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Trinkets
Win %
Buy %

54%
102%

67%
34%

60%
9%
Vayne Boots
Win %
Buy %

54%
98%