Tier: CWin45.61%Role21.02%Pick0.51%Ban1.15%Games: 364KDA: 2.43Score: 46.97
Karthus Mid Lane is ranked C Tier and has a 45.61% win rate in LoL Patch 9.24. We've analyzed 364 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Rod of Ages, Sorcerer's Shoes, Morellonomicon, Zhonya's Hourglass, Rabadon's Deathcap, and Void Staff. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Health Potion, Doran's Ring, Refillable Potion, Boots of Speed, and Warding Totem (Trinket). Karthus's Best Mid Lane matchups include Ahri, Corki, and Gangplank. Karthus's Best Mid Lane counters are Orianna, Twisted Fate, and Teemo.
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Karthus Summoner Spells


Win %
Pick %
49%
87%
50%
45%

49%
38%

49%
21%

48%
6%

80%
1%
Karthus Starting Items

48%

50%

59%

65%

48%
Karthus Runes
Win %
Pick %
55%
29%
50%
24%
48%
9%
52%
6%
Karthus Items

51%

49%

52%

53%

55%

61%

49%

66%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Trinkets
Win %
Buy %

49%
101%

43%
16%

24%
6%
Karthus Boots
Win %
Buy %

49%
92%

41%
5%

100%
0%

0%
0%

0%
1%