Vayne Mid Lane is ranked Off Meta Tier and has a 51.59% win rate in LoL Patch 8.24. We've analyzed 445 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of the Ruined King, Guinsoo's Rageblade, Rapid Firecannon, Phantom Dancer, and Infinity Edge. For runes, the strongest choice is Precision (Primary) with Fleet Footwork (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Long Sword, and Warding Totem (Trinket). Vayne's Best Mid Lane matchups include Lissandra, Aurelion Sol, and Heimerdinger. Vayne's Best Mid Lane counters are Brand, Malzahar, and Tryndamere.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Jungle Duo Queue Champions for Vayne Mid Lane(49% - 51% win rate with Vayne)
Even Mid Lane Matchups for Vayne Mid Lane(49% - 51% win rate for Vayne)
