Cassiopeia Mid Lane is ranked S+ Tier and has a 53.74% win rate in LoL Patch 8.24. We've analyzed 10235 Cassiopeia Mid Lane games to compile our statistical Cassiopeia Build Guide. For items, our build recommends: Luden's Echo, Rylai's Crystal Scepter, Liandry's Torment, Morellonomicon, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Health Potion, Doran's Ring, Corrupting Potion, Refillable Potion, and Warding Totem (Trinket). Cassiopeia's Best Mid Lane matchups include Gangplank, Kled, and Quinn. Cassiopeia's Best Mid Lane counters are Wukong, Zilean, and Anivia.
Cassiopeia Summoner Spells






Cassiopeia Starting Items





Cassiopeia Runes
Cassiopeia Items








Cassiopeia Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Cassiopeia Trinkets


