Tier: Off MetaWin43.21%Role0.98%Pick0.12%Ban7.25%Games: 81KDA: 1.73Score: 44.84
Vayne Mid Lane is ranked Off Meta Tier and has a 43.21% win rate in LoL Patch 25.08. We've analyzed 81 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Kraken Slayer, Trinity Force, Guinsoo's Rageblade, and Terminus. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Barrier. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include Lux and Zed. Vayne's Best Mid Lane counters are Ekko, Malzahar, and Veigar.
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Vayne Summoner Spells


Win %
Pick %
43%
100%
52%
36%

39%
38%

33%
11%

50%
7%

100%
1%
Vayne Starting Items
Win %
Buy %



46%
80%


40%
6%
Vayne Runes
Win %
Pick %
44%
61%
42%
12%
94%
3%
60%
2%
Vayne Items

44%

45%

53%

64%

46%

56%

43%

50%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order






























Vayne Trinkets
Win %
Buy %

43%
89%

67%
11%

31%
16%
Vayne Boots
Win %
Buy %

44%
88%

50%
5%

0%
1%
Vayne Situational Items
Win %
Buy %

44%
20%

45%
14%

80%
6%

100%
4%

50%
5%

100%
2%