Tier: Off MetaWin25.44%Role1.20%Pick0.10%Ban3.50%Games: 27KDA: 1.22Score: 41.35
Vayne Mid Lane is ranked Off Meta Tier and has a 25.44% win rate in LoL Patch 25.07. We've analyzed 27 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, The Collector, Infinity Edge, Guinsoo's Rageblade, and Terminus. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Ghost. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include LeBlanc.
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Vayne Summoner Spells


Win %
Pick %
52%
100%
63%
59%

50%
22%

25%
15%

0%
4%
Vayne Starting Items
Win %
Buy %



57%
85%


3

100%
4%
Vayne Runes
Win %
Pick %
47%
64%
79%
12%
70%
6%
0%
4%
Vayne Items

48%

53%

75%

75%

83%

60%

57%

100%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order

1055

1001

1042


3006

1053

1043

1037


3153

3134

1037

1018


6676

1018

1038

1055

1037


3031

1043

1052


3124

1043


3302


3172
Vayne Trinkets
Win %
Buy %

57%
78%

44%
67%
Vayne Boots
Win %
Buy %

48%
78%

100%
15%
Vayne Situational Items
Win %
Buy %

60%
19%

67%
11%

100%
7%

100%
7%

40%
19%

100%
4%