Tier: Off MetaWin50.12%Role1.92%Pick0.15%Ban5.80%Games: 5389KDA: 1.85Score: 49.14
Vayne Mid Lane is ranked Off Meta Tier and has a 50.12% win rate in LoL Patch 25.04. We've analyzed 5389 Vayne Mid Lane games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Kraken Slayer, Guinsoo's Rageblade, Wit's End, and Terminus. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Flash and Ghost. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Vayne's Best Mid Lane matchups include Swain, Kassadin, and Aurelion Sol. Vayne's Best Mid Lane counters are Kennen, Naafiri, and Zilean.
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Vayne Summoner Spells


Win %
Pick %
50%
99%
51%
40%

50%
30%

46%
14%

49%
6%

43%
6%
Vayne Starting Items
Win %
Buy %



50%
79%



48%
7%
Vayne Runes
Win %
Pick %
51%
60%
46%
15%
47%
4%
43%
2%
Vayne Items

50%

51%

52%

56%

53%

58%

49%

58%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order






























Vayne Trinkets
Win %
Buy %

49%
83%

51%
38%

52%
10%
Vayne Boots
Win %
Buy %

50%
81%

53%
6%

48%
5%

50%
2%

47%
1%

46%
1%
Vayne Situational Items
Win %
Buy %

56%
15%

55%
8%

54%
7%

53%
6%

56%
5%

48%
4%