Tier: BWin53.64%Role19.41%Pick0.39%Ban1.12%Games: 3045KDA: 2.19Score: 50.45
Karthus Mid Lane is ranked B Tier and has a 53.64% win rate in LoL Patch 10.25. We've analyzed 3045 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Zhonya's Hourglass, Demonic Embrace, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Doran's Ring, Health Potion, and Oracle Lens. Karthus's Best Mid Lane matchups include Riven, Neeko, and Kog'Maw. Karthus's Best Mid Lane counters are Xerath, Kassadin, and Rumble.
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Karthus Summoner Spells


Win %
Pick %
52%
99%
54%
57%

48%
24%

51%
11%

47%
6%

37%
1%
Karthus Starting Items
Win %
Buy %


2

53%
50%


2

50%
36%
Karthus Runes
Win %
Pick %
53%
57%
52%
14%
57%
2%
43%
2%
Karthus Items

54%

53%

52%

54%

59%

58%

52%

53%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order

























Karthus Trinkets
Win %
Buy %

52%
88%

54%
25%

53%
10%
Karthus Boots
Win %
Buy %

53%
93%

40%
4%

64%
1%

58%
1%

75%
0%

67%
0%
Karthus Mythic Items
Win %
Buy %

54%
67%

47%
27%

52%
5%

68%
1%

41%
1%

0%
0%