Tier: S+Win71.05%Role23.31%Pick1.10%Ban2.12%Games: 38KDA: 3.30Score: 80.24
Karthus Lane is ranked S+ Tier and has a 71.05% win rate in LoL Nexus Blitz Patch 13.23. We've analyzed 38 Karthus Lane games to compile our statistical Karthus Nexus Blitz Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Shadowflame, Morellonomicon, Demonic Embrace, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Amplifying Tome and Stealth Ward. Karthus's Best Nexus Blitz Lane matchups include Pantheon and Ziggs. Karthus's Best Nexus Blitz Lane counters are Vladimir.
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Karthus Summoner Spells

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Win %
Pick %
69%
92%
75%
42%
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67%
39%

80%
13%

100%
8%

50%
5%
Karthus Starting Items
Win %
Buy %


89%
24%

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2

73%
29%
Karthus Runes
Win %
Pick %
62%
36%
71%
37%
100%
8%
67%
8%
Karthus Items
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74%

72%

77%

100%

100%

63%

70%

100%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order




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
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

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





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
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Karthus Trinkets
Win %
Buy %

70%
97%
Karthus Boots
Win %
Buy %

72%
95%
Karthus Mythic Items
Win %
Buy %

74%
82%

67%
16%