Seraphine Lane is ranked S+ Tier and has a 53.32% win rate in LoL Nexus Blitz Patch 13.23. We've analyzed 671 Seraphine Lane games to compile our statistical Seraphine Nexus Blitz Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Rylai's Crystal Scepter, Archangel's Staff, Cosmic Drive, and Rabadon's Deathcap. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Doran's Ring, Health Potion, and Oracle Lens. Seraphine's Best Nexus Blitz Lane matchups include Aurelion Sol, Janna, and Gwen. Seraphine's Best Nexus Blitz Lane counters are Milio, Renekton, and Gangplank.
Seraphine Summoner Spells






Seraphine Starting Items






Seraphine Runes
Seraphine Items








Seraphine Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Seraphine Item Purchase Order

























Seraphine Trinkets



Seraphine Boots






Seraphine Mythic Items





