Karthus Lane is ranked D Tier and has a 43.64% win rate in LoL Nexus Blitz Patch 13.23. We've analyzed 55 Karthus Lane games to compile our statistical Karthus Nexus Blitz Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Zhonya's Hourglass, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Tear of the Goddess, Health Potion, and Stealth Ward. Karthus's Best Nexus Blitz Lane matchups include Kai'Sa, Mordekaiser, and Yasuo. Karthus's Best Nexus Blitz Lane counters are Miss Fortune, Cassiopeia, and Darius.
Karthus Summoner Spells
Karthus Starting Items
Karthus Runes
Karthus Items
Karthus Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Karthus Item Purchase Order
3200
1100
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30003600Karthus Trinkets
Karthus Boots
Karthus Mythic Items
Average Lane Duo Queue Champions for Karthus Lane in Nexus Blitz(49% - 51% win rate with Karthus)
Average Jungle Duo Queue Champions for Karthus Lane in Nexus Blitz(49% - 51% win rate with Karthus)
Even Lane Matchups for Karthus Lane in Nexus Blitz(49% - 51% win rate for Karthus)
Even Jungle Matchups for Karthus Lane in Nexus Blitz(49% - 51% win rate for Karthus)
