Seraphine Lane is ranked S+ Tier and has a 62.08% win rate in LoL Nexus Blitz Patch 13.23. We've analyzed 429 Seraphine Lane games to compile our statistical Seraphine Nexus Blitz Build Guide. For items, our build recommends: Ionian Boots of Lucidity, Liandry's Anguish, Rylai's Crystal Scepter, Archangel's Staff, Cosmic Drive, and Morellonomicon. For runes, the strongest choice is Sorcery (Primary) with Summon Aery (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Tear of the Goddess, Health Potion, and Oracle Lens. Seraphine's Best Nexus Blitz Lane matchups include Kalista, Ahri, and Anivia. Seraphine's Best Nexus Blitz Lane counters are Camille, Galio, and Shaco.
Seraphine Summoner Spells






Seraphine Starting Items






Seraphine Runes
Seraphine Items








Seraphine Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Seraphine Item Purchase Order
























Seraphine Trinkets



Seraphine Boots






Seraphine Mythic Items





