Karthus Lane is ranked C Tier and has a 52.51% win rate in LoL Nexus Blitz Patch 10.25. We've analyzed 9912 Karthus Lane games to compile our statistical Karthus Nexus Blitz Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Zhonya's Hourglass, Morellonomicon, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Tear of the Goddess, Health Potion, and Stealth Ward. Karthus's Best Nexus Blitz Lane matchups include Rek'Sai, Evelynn, and Shyvana. Karthus's Best Nexus Blitz Lane counters are Skarner, Alistar, and Kled.
Karthus Summoner Spells
Karthus Starting Items
Karthus Runes
Karthus Items
Karthus Skill Order
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 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Karthus Item Purchase Order
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25003800Karthus Trinkets
Karthus Boots
Karthus Mythic Items
Average Lane Duo Queue Champions for Karthus Lane in Nexus Blitz(49% - 51% win rate with Karthus)
Below Average Lane Duo Queue Champions for Karthus Lane in Nexus Blitz(under 49% win rate with Karthus)
Average Jungle Duo Queue Champions for Karthus Lane in Nexus Blitz(49% - 51% win rate with Karthus)
Below Average Jungle Duo Queue Champions for Karthus Lane in Nexus Blitz(under 49% win rate with Karthus)
Best Lane Champions to Counter Karthus Lane(under 49% win rate for Karthus)
Even Lane Matchups for Karthus Lane in Nexus Blitz(49% - 51% win rate for Karthus)
Best Jungle Champions to Counter Karthus Lane(under 49% win rate for Karthus)
Even Jungle Matchups for Karthus Lane in Nexus Blitz(49% - 51% win rate for Karthus)