Seraphine Lane is ranked S+ Tier and has a 61.01% win rate in LoL Nexus Blitz Patch 13.23. We've analyzed 23372 Seraphine Lane games to compile our statistical Seraphine Nexus Blitz Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Rylai's Crystal Scepter, Archangel's Staff, Cosmic Drive, and Rabadon's Deathcap. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Doran's Ring, Health Potion, and Oracle Lens. Seraphine's Best Nexus Blitz Lane matchups include Udyr, Rek'Sai, and Lulu. Seraphine's Best Nexus Blitz Lane counters are Cho'Gath, Jax, and Alistar.
Seraphine Summoner Spells






Seraphine Starting Items






Seraphine Runes
Seraphine Items








Seraphine Skill Order
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![]() | R | R | R |
Seraphine Item Purchase Order

























Seraphine Trinkets



Seraphine Boots






Seraphine Mythic Items






Best Lane Duo Queue Champions for Seraphine Lane in Nexus Blitz(over 51% win rate with Seraphine)



















































































































Best Jungle Duo Queue Champions for Seraphine Lane in Nexus Blitz(over 51% win rate with Seraphine)


















































































































Best Lane Matchups for Seraphine Lane in Nexus Blitz(over 51% win rate for Seraphine)
















































































































































Best Jungle Matchups for Seraphine Lane in Nexus Blitz(over 51% win rate for Seraphine)

































































































































