Tier: Off MetaWin58.52%Role5.59%Pick0.12%Ban3.43%Games: 889KDA: 4.06Score: 64.55
Karthus Mid Lane is ranked Off Meta Tier and has a 58.52% win rate in LoL Patch 25.06. We've analyzed 889 Karthus Mid Lane games to compile our statistical Karthus Build Guide. For items, our build recommends: Blackfire Torch, Malignance, Sorcerer's Shoes, Liandry's Torment, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Exhaust. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Mid Lane matchups include Cassiopeia, Twisted Fate, and Ekko. Karthus's Best Mid Lane counters are Veigar, Qiyana, and Ziggs.
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Karthus Summoner Spells


Win %
Pick %
47%
79%
51%
39%

44%
44%

50%
28%

42%
6%

60%
1%
Karthus Starting Items
Win %
Buy %


2

48%
70%


2

25%
2%
Karthus Runes
Win %
Pick %
47%
48%
49%
20%
44%
8%
46%
4%
Karthus Items

51%

43%

50%

52%

51%

52%

46%

53%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order


























Karthus Trinkets
Win %
Buy %

46%
83%

52%
34%

56%
8%
Karthus Boots
Win %
Buy %

50%
77%

33%
6%

50%
1%

60%
1%

50%
0%

100%
0%
Karthus Situational Items
Win %
Buy %

48%
22%

54%
14%

52%
11%

56%
5%

51%
5%

57%
4%